Vol.76, No.3 March 2014
Explanation of the cover photographs
Effects of Polyethylene Glycol Administration and Bone Marrow Stromal Cell Transplantation Therapy in Spinal Cord Injury Mice
Yasutaka Oda et al. (pp. 415–421)
Immunohistochemical study of the thoracic cord from the control group 4 weeks after surgical procedures. Spinal cord section demonstrated double immunofluorescence of GFAP (green), MAP-2 (red) and cell nuclei (blue). In the control-group, few neuronal cells were observed in the glial scar.
In the BMSC-group, neuronal cells migrated toward the glial scar from the region rostral of lesion site. MAP-2-positive cells (arrows). GFAP-positive cells (arrowheads). In the PEG-group, a few neuronal cells were observed in the glial scar compared to control-group. MAP-2-positive cell (arrow). In the BMSC+PEG-group, many neuronal cells had aggressively migrated toward the glial scar from the region rostral of the lesion site, which was significantly different from the control-group. MAP-2-positive cells (arrows). GFAP-positive cells (arrowheads). Bar=750 μm
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